Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography

Determination of three ultraviolet filters in sunscreen formulations and from skin penetration studies by high-performance liquid chromatography

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An analytical procedure to quantify 3-benzophenone, octylmethoxycinnamate and octylsalicylate was validated and employed to assess these ultraviolet filters in sunscreen formulations and from skin penetration studies.The effect of the vehicle on the skin retention of feline 1-hcpch vaccine these filters was investigated.HPLC and extraction procedure were found to be reliable when obtaining data for the sunscreen formulations and for evaluation skin penetration.The results demonstrated that a cream gel generated higher epidermal concentrations of these filters than a lotion or cream-based formulation.Additionally, when comparing the skin retentions of each filter using the same formulation, 3-benzophenone earthbath facial wipes showed the highest skin retention.